Clinical evidence

Peptide Evidence Level Checker

Compare the strength of human, investigational, and preclinical evidence behind peptide compounds.

Evidence tiers follow established clinical research hierarchies
Gold Standard Human Evidence

Tier 1: FDA-Approved Human Phase 3 RCTs

Supported by multi-center, double-blind, randomized controlled trials in thousands of human subjects (n > 1,000) demonstrating statistical efficacy and quantifiable safety profiles.

Semaglutide

Evidence
SUSTAIN 1-10, STEP 1-8, SELECT (n > 25,000)

Finding
14.9% mean weight loss; 20% MACE CVD risk reduction

Tirzepatide

Evidence
SURPASS 1-6, SURMOUNT 1-4 (n > 15,000)

Finding
20.9% mean weight loss; profound glycemic normalization

Bremelanotide (PT-141)

Evidence
RECONNECT Trials (n=1,247)

Finding
Statistically significant improvement in HSDD desire scores

Tesamorelin

Evidence
Phase 3 Lipodystrophy Programs (n=806)

Finding
15-18% reduction in visceral adipose tissue (VAT) via MRI