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GuidePepsin and other enzymes dismantle peptides in the stomach within minutes. While oral semaglutide succeeds due to a specific permeation enhancer, standard capsules deliver negligible systemic exposure. This is the core challenge for any.
News WireThe FDA cleared oral semaglutide 25 mg as the first GLP-1 pill for weight loss on December 22, 2025. Truveta data shows the pill drew thousands of new patients into GLP-1 therapy. Eli Lilly's orforglipron awaits FDA review.
News WireAizen Therapeutics, a San Diego-based AI biotech spun out of Caltech, has entered a multi-program collaboration with an undisclosed public partner. The deal includes upfront funding and up to $100 million in milestone payments per target.