Clinical Peptide Monographs & Regulatory Directory
Comprehensive, evidence-based monographs covering biochemical mechanisms, Phase 3 human clinical trials, FDA statutory status, and pharmacological safety profiles.
Semaglutide
(Ozempic, Wegovy)Semaglutide is a long-acting synthetic glucagon-like peptide-1 (GLP-1) receptor agonist engineered with an Aib8 substitution to resist DPP-4...
Tirzepatide
(Mounjaro, Zepbound)Tirzepatide is a synthetic 39-amino-acid unimolecular dual agonist engineered to activate both the glucose-dependent insulinotropic polypept...
Retatrutide
(LY3437943 (Investigational))Retatrutide (LY3437943) is an investigational single peptide with triple agonist activity at the GLP-1, GIP, and glucagon (GCGR) receptors. ...
BPC-157
(Body Protection Compound-157, PL 14736)BPC-157 is a 15-amino-acid synthetic sequence derived from a naturally occurring protective peptide isolated from human gastric juice. In pr...
TB-500 (Thymosin Beta-4 Fragment)
(Synthetic Thymosin Beta-4, Ac-LKKTETQ)TB-500 is a synthetic fragment containing the actin-binding heptapeptide sequence (Ac-LKKTETQ) of Thymosin Beta-4 ($Teta4$), a 43-amino-aci...
CJC-1295
(Mod GRF 1-29, DAC:GRF)CJC-1295 is a synthetic 29-amino-acid analog of human GHRH (1-29) with four substituted amino acids that resist dipeptidyl peptidase-4 (DPP-...
Ipamorelin
(NNC 26-0161)Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) that acts as a selective agonist at the ghrelin/growth hormone secret...
GHK-Cu
(Copper Tripeptide-1, Gly-His-Lys Copper)GHK-Cu is a naturally occurring tripeptide (glycyl-L-histidyl-L-lysine) chelated with copper (Cu2+). Discovered in human plasma in 1973 by D...
Melanotan II
(MT-2, Melanocortin Agonist)Melanotan II is a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone ($alpha$-MSH). It acts as a potent non-select...
Bremelanotide (PT-141)
(Vyleesi)Bremelanotide (PT-141) is a synthetic cyclic heptapeptide and active metabolite of Melanotan II that selectively activates central melanocor...
Tesamorelin
(Egrifta, Egrifta SV)Tesamorelin is a synthetic 44-amino-acid peptide consisting of the complete human GHRH sequence attached to a trans-3-hexenoyl fatty acid mo...
MOTS-c
(Mitochondrial Open Reading Frame of the 12S rRNA-c)MOTS-c is a 16-amino-acid peptide encoded within the mitochondrial 12S ribosomal RNA genome. It functions as an endocrine-like mitochondrial...